GIFT Faculty
Weiliang Xia
Tenured Full Professor, Global Institute of Future Technology, SJTU
Ph.D., The University of Hong Kong (joint training at the Rockefeller University)
Office Location :Room 104, East Wing of Yue-kong Pao Library
Tel :+86-021-54741175
Email :wlxia@sjtu.edu.cn
Education

1998-1999,Tsinghua University,Biology and Biotechnology

1999-2002,The University of Hong Kong,Animal and Plant Biotechnology,B.Sc

2002-2006,The University of Hong Kong with joint pre-doctoral program at The Population Council, The Rockefeller University,Molecular and Cell Biology,Ph.D

Work Experience

2026 - Pres.,Global Institute of Future Technology , Shanghai Jiao Tong University,Tenured Full Professor

2021 - 2025, School of Biomedical Engineering, Shanghai Jiao Tong University,Tenured Full Professor

2014 - 2021, School of Biomedical Engineering, Shanghai Jiao Tong University,Professor

2012 - 2014, School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University,Special Investigator (Tenure-track Associate Professor)

2008 - 2011, Med-X Research Institute, Shanghai Jiao Tong University,Associate Professor

2007 - 2008, University of California at San Francisco,Postdoctoral Associates

Research Fields

With interdisciplinary research of biomedicine and engineering as the central paradigm, Xia group studies the complex regulatory mechanisms of life systems, focusing on aging, cancer and extracellular vesicles to investigate the mechanisms and novel therapeutic targets for major diseases such as lung cancer, and develop new theranostic tools.

Honors and Awards

“Rising Star” Award (2009), Science and Technology Commission of Shanghai

Outstanding Teachers Award, Second Prize (2012-2013), Shanghai Jiao Tong University

First Prize in Teaching Achievement (2013), Shanghai Jiao Tong University

Second Prize in Teaching Achievement (2013), Shanghai Municipality

“Candle Award”, First Prize, Shanghai Jiao Tong University (2016)

Tang Lixin Scholar, Shanghai Jiao Tong University (2019)

Grand Prize in Teaching Achievement (2020), Shanghai Jiao Tong University

Second Prize in Teaching and Nurturing (Group Prize, 2020), Shanghai Jiao Tong University

First Prize in Teaching Achievement (2021), Shanghai Jiao Tong University

Outstanding Service for Top-notch Talents Cultivation Program 2.0, Ministry of Education, China

Second Prize, Award of Science and Technology for Medicine, China (2021)

First Prize in Teaching Achievement (2022), Shanghai Municipality

National Prize in Teaching Achievement (2023, second prize), China

2025 Outstanding Contribution Award by Zhiyuan College (honors college), Shanghai Jiao Tong University

Professional Service

Executive Editor (China) for Extracellular Vesicles and Circulating Nucleic Acids

Selected Publications (10 selected in last 3 years)

1. Li F, Li Z, Han Q, Chen Y, Ji W, Yang Y, Lu S, Xia W*. Enhanced autocrine FGF19/FGFR4 signaling drives the progression of lung squamous cell carcinoma, which responds to mTOR inhibitor AZD2104. Oncogene. 2020; 37:3507–3521.

2. Yan L, Li H*, Xia W*. Bioglass could increase cell membrane fluidity with ion products to develop its bioactivity. Cell Proliferation. 2020;53: e12906.

3. Han Q, Xie QR, Li F, Cheng Y, Wu T, Wong AS, Sha J*, Xia W*. Targeted inhibition of SIRT6 via engineered exosomes impairs tumorigenesis and metastasis in prostate cancer. Theranostics. 2021;11:6526-6541

4. Cheng Y, Lu X, Li F, Chen Z, Zhang Y, Han Q, Zeng Q, Wu T, Li Z, Lu S, Williams C, Xia W*.NDFIP1 limits cellular TAZ accumulation via exosomal sorting to inhibit NSCLC proliferation Protein Cell 2023;14:123-136.

5. Wu T, Zhang Y, Han Q, Lu X, Cheng Y, Chen J, Sha J, Xia W*. Klotho-beta attenuates Rab8a-mediated exosome regulation and promotes prostate cancer progression. Oncogene. 2023;42:2801-2815.

6. Lu X, Han Q, Chen J, Wu T, Cheng Y, Li F, Xia W*. Celery (Apium graveolens L.) Exosome-like Nanovesicles as a New-Generation Chemotherapy Drug Delivery Platform against Tumor Proliferation. Journal of Agriculture and Food Chemistry. 2023; 71:8413-8424.

7. Zhang F, Lu X, Zhu X, Yu Z, Xia W*, Wei X*. Real-Time Monitoring of Small Extracellular Vesicles (sEVs) by In vivo Flow Cytometry. Journal of Extracellular Vesicles. 2024;13:e70003.

8. Guo Z, Xia W*. Isolation of circulating tumor cells: recent progress and future perspectives. Med-X. 2024; 2:28.

9. Chen Z, Ji W, Feng W, Cui J, Wang Y, Li F, Chen J, Guo Z, Xia L, Zhu X, Niu X, Zhang Y, Li Z, Wong AS, Lu S*, Xia W*. PTPRT loss enhances anti-PD-1 therapy efficacy by regulation of STING pathway in non-small cell lung cancer. Science Translational Medicine. 2024 Sep 4;16(763):eadl3598.

10. Xiao H, Xia W*. Hemoglobin-Based Oxygen Carrier: What we have learned and where we are heading? Protein Cell .2026 Mar 24:pwag019.

Course Taught (Recent 5 Years)

Cell Biology and Histology (English)

Cell Biology (Honor)

Cell Biology Tutorial

Exploratory Laboratory Course